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Publications
There are hundreds of clinical trials in cardiology. Learning each trial is near impossible, however a select few should be well known to clinicians in their field of research. Included in our publication section are some landmark trials in arrhythmia and stroke, links to the original publication and other related resources.
Publications
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Diagnostic accuracy and yield of screening tests for atrial fibrillation in the family practice setting: a multicentre cohort study
Read PublicationCMAJ Open. 2018 Aug 2;6(3):E308-E315. doi: 10.9778/cmajo.20180001. Print 2018 Jul-Sep.
F. Russell Quinn, David J. Gladstone, Noah M. Ivers, Roopinder K. Sandhu, Lisa Dolovich, Andrea Ling, Juliet Nakamya, Chinthanie Ramasundarahettige, Paul A. Frydrych, Sam Henein, Ken Ng, Valerie Congdon Richard V. Birtwhistle, Richard Ward, Jeffrey S. Healey
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Rivaroxaban for Stroke Prevention after Embolic Stroke of Undetermined Source
Read PublicationN Engl J Med. 2018 Jun 7;378(23):2191-2201. doi: 10.1056/NEJMoa1802686. Epub 2018 May 16.
R.G. Hart, M. Sharma, H. Mundl, S.E. Kasner, S.I. Bangdiwala, S.D. Berkowitz, B. Swaminathan, P. Lavados, Y. Wang, Y. Wang, A. Davalos, N. Shamalov, R. Mikulik, L. Cunha, A. Lindgren, A. Arauz, W. Lang, A. Czlonkowska, J. Eckstein, R.J. Gagliardi, P. Amarenco, S.F. Ameriso, T. Tatlisumak, R. Veltkamp, G.J. Hankey, D. Toni, D. Bereczki, S. Uchiyama, G. Ntaios, B.-W. Yoon, R. Brouns, M. Endres, K.W. Muir, N. Bornstein, S. Ozturk, M.J. O’Donnell, M.M. De Vries Basson, G. Pare, C. Pater, B. Kirsch, P. Sheridan, G. Peters, J.I. Weitz, W.F. Peacock, A. Shoamanesh, O.R. Benavente, C. Joyner, E. Themeles, and S.J. Connolly, for the NAVIGATE ESUS Investigators
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High prevalence of modifiable stroke risk factors identified in a pharmacy-based screening programme
Read PublicationOpen Heart 2016;3:e000515. doi:10.1136/openhrt-2016-000515.
Roopinder K Sandhu, Lisa Dolovich, Bishoy Deif, Walid Barake, Gina Agarwal, Alex Grinvalds, Ting Lim, F. Russell Quinn, David Gladstone, David Conen, Stuart J. Connolly, Jeff S. Healey
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Randomized Assessment of Rapid Endovascular Treatment of Ischemic Stroke
Full PublicationNew England Journal of Medicine, 2015 Mar 12;372(11):1019-30.
Goyal M, Demchuk AM, Menon BK, Eesa M, Rempel JL, Thornton J, Roy D, Jovin TG, Willinsky RA, Sapkota BL, Dowlatshahi D, Frei DF, Kamal NR, Montanera WJ, Poppe AY, Ryckborst KJ, Silver FL, Shuaib A, Tampieri D, Williams D, Bang OY, Baxter BW, Burns PA, Choe H, Heo JH, Holmstedt CA, Jankowitz B, Kelly M, Linares G, Mandzia JL, Shankar J, Sohn SI, Swartz RH, Barber PA, Coutts SB, Smith EE, Morrish WF, Weill A, Subramaniam S, Mitha AP, Wong JH, Lowerison MW, Sajobi TT, Hill MD; ESCAPE Trial Investigators.
To learn more go to www.escapetrial.org or http://cumming.ucalgary.ca/escape-stroke
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Embolic strokes of undetermined source: the case for a new clinical construct
Read PublicationLancet Neurol. 2014 Apr;13(4):429-38.
Hart RG1, Diener HC2, Coutts SB3, Easton JD4, Granger CB5, O’Donnell MJ6, Sacco RL7, Connolly SJ8; Cryptogenic Stroke/ESUS International Working Group.
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Review: Screening for Undiagnosed Atrial Fibrillation in the community
Read PublicationCurrent Opinion in Cardiology. 2014 Jan;29(1):28-35.
Quinn FR, Gladstone D.
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Rationale and Design of the Prorgam for the Identification of “Actionable” Atrial Fibrillation(PIAAF): Systematic Identification to Detect Previously Undiagnosed or Untreated AF in the Community
Read PublicationCanadian Journal of Cardiology. Volume 30, 2014
RK Sandhu, FR Quinn, N Ivers, G Agarwal, R Tsuyuki, DJ Gladstone, L Dolovich, J Healey
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Radiofrequency Ablation vs Antiarrhythmic Drugs as First-Line Treatment of Paroxysmal Atrial Fibrillation (RAAFT II)
Read PublicationJAMA. 2014;311(7):692-700.
Carlos A. Morillo; Atul Verma; Stuart J. Connolly; Karl H. Kuck; Girish M. Nair; Jean Champagne; Laurence D. Sterns; Heather Beresh; Jeffrey S. Healey; Andrea Natale ; for the RAAFT-2 Investigators
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Left Atrial Appendage Occlusion Study II (LAAOS II)
Read PublicationCanadian Journal of Cardiology, 2013.
Richard P. Whitlock, Jessica Vincent, Mary Helen Blackall, Jack Hirsh, Stephen Fremes, Richard Novick, P.J. Devereaux, Kevin Teoh, Andre Lamy, Stuart J. Connolly, Salim Yusuf, Michel Carrier, Jeff S. Healey.
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Discerning the Incidence of Symptomatic and Asymptomatic Episodes of Atrial Fibrillation Before and After Catheter Ablation (DISCERN AF)
Read PublicationJAMA Internal Medicine 2013;173(2):149-156.
Atul Verma; Jean Champagne; John Sapp; Vidal Essebag; Paul Novak; Allan Skanes; Carlos A. Morillo; Yaariv Khaykin; David Birnie.
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Validity of Administrative Data for Identifying Patients Who Have Had a Stroke or Transient Ischemic Attack Using EMRALD as a Reference Standard
Read PublicationCanadian Journal of Cardiology, 2013
Karen Tu, Myra Wang, Jacqueline Young, Diane Green, Noah M. Ivers, Debra Butt, Liisa Jaakkimainen, Moira K. Kapral.
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Subclinical Atrial Fibrillation and the Risk of Stroke (ASSERT)
Read PublicationThe New England Journal of Medicine 2012;366:120-129. January 12, 2012
Jeff S. Healey, Stuart J. Connolly, Micheal R. Gold, Carsten W. Israel, Isabelle C. Van Gelder, Alessandro Capucci, C.P. Lau, Eric Fain, Sean Yang, Christophe Bailleul, Carlos A. Morillo, Mark Carlson, Ellison Themeles, Elizabeth S. Kaufman, Stefan H. Hohnloser for the ASSERT Investigators.
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Shaping the Future of Vascular Health: An Integrated Vascular Health Blueprint for Ontario
Download PDF of Publication2012
Cardiac Care Network of Ontario, Heart and Stroke Foundation, Ontario Stroke Network.
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Improving cardiovascular health at population level: 39 community cluster randomised trial of Cardiovascular Health Awareness Program (CHAP)
Read PublicationThe BMJ 2011; 342
Janusz Kaczorowski, Larry W Chambers, Lisa Dolovich, J Michael Paterson, Tina Karwalajtys, Tracy Gierman, Barbara Farrell, Beatrice McDonough, Lehana Thabane, Karen Tu, Brandon Zagorski, Ron Goeree, Cheryl a Levitt, William Hogg, Stephanie Laryea, Megan Ann Carter, Dana Cross, Rolf J Sabaldt.
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Cardiovascular Health Awareness Program (CHAP): a community cluster-randomised trial among elderly Canadians.
Read PublicationPreventive Medicine 2008 Jun;46(6):537-44.
Kaczorowski J, Chambers LW, Karwalajtys T, Dolovich L, Farrell B, McDonough B, Sebaldt R, Levitt C, Hogg W, Thabane L, Tu K, Goeree R, Paterson JM, Shubair M, Gierman T, Sullivan S, Carter M.
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Innovative strategic Canadian research training from TomorrOw’s Research Cardiovascular Health Care Professionals (TORCH)
Download PDF of PublicationClinical & Investigative Medicine. 2004 Feb;27(1):33-41.
Armstrong PW, Ezekowitz C, Michelakis E, Anderson T, Archer S, Ghali W, Hayward R, Jensen L, Lopaschuk G, Sheldon R.